| Sample |
PSI |
Passes |
Results |
Veterinary vaccine
25% W/O vaccine with inactivated bacteria |
1000 |
1 |
All particles < 1.0 microns
-Average particle size: 0.1µ
-Antigen efficacy increase 5-10 times |
Vaccine adjuvant for influenza virus vaccine
Tetronic 1501
Squalane
Tween 80
P.B.S. |
2.5%
5.0%
0.2%
q.s. |
|
10000 |
2-10 |
Particle size: all < 0.3µ
Patented adjuvant. |
| Liposomes encapsulating a dye marker for diagnostic tests. |
4000
4000
|
1
4
|
0.3-0.4µ liposomes
Distribution tightened. Mat'l run at 45C. Above results considered success since tight size control required to produce a reliable diagnostic test kit.
|
|
|
|
|
| 20 % Soy Lecithin Liposomes |
5000
10000
15000
|
1
1
1
|
Particle size: 0.118µ
Particle size: 0.101µ
Particle size: 0.091µ
|
Incomplete Freud's Adjuvant
(W/O emulsion)
Lt mineral oil
Arlacel A
D.I. Water
Tween 80 |
72.0%
8.0%
19.2%
0.8% |
|
200 |
1 |
Particle size: most 1-3µ, some 2-4µ, very few at 5µ.
No coalescence of water droplets seen after several weeks of stability testing. |
Processors
