M-110L Microfluidizer Processor:
* Produce stable micro-emulsions & dispersions
• Increase yield in cell disruption
• Create finer micro-encapsulations

Microfluidics produces patented Microfluidizer® Processor equipment with high-pressure, fixed-geometry interaction chambers that impart intense energy to product formulations. The M-110L produces up to 18,000 psi with standard lab air, for premium results at an affordable cost.

Microfluidizer Processors combine superior, scalable results with easy handling and small footprint:

• Can produce 18,000 psi process pressure with less than 25 scfm air using 7.5 HP compressor
  
• Can process samples as small as 14 ml with 12 ml typical recovery
  
• Process may be continuous, batch or recirculation
  
• Available in fully autoclavable configuration (place entire unit in autoclave without disassembly)
  
• Fully CE compliant base unit; inherently explosion-proof
  
• R&D process results will scale to higher volume Microfluidizer process equipment

Download M-110L product info as a PDF

M-110L Specifications

• Pressure range up to 18,000 psi
• Flowrate Range up to 270 ml/min @ 18,000 psi
• Feed Temperature Range -15°F to 165°F (-25°C to 75°C)
• Air Compressor Requirements compressor size and air requirements will vary from 7.5 HP (80 psi, 28 SCFM) to 15 HP (80 psi, 57 SCFM) depending upon selection of interaction chamber
• Minimum Sample Size (with 25 ml reservoir) 14 ml with up to 12 ml recovery
• Dimensions 23"L x 15"W x 26"H ( 60 x 39 x 68 cm)
• Weight 58 lbs. (26.4 kg)

M-110L Standard Features

• Ceramic interaction chamber
  
• CE compliant
  
• Polished stainless steel full system enclosure
  
• Small diameter tubing for minimum holdup volume
  
• 200 ml glass reservoir
  
• Removable recirculation loop
  
• UHMWPE (Ultra High Molecular Weight Polyethylene) plunger seal
  
• Spare parts kit
  
• Removable cooling coil

M-110L Options

• 400 ml and/or 1 liter stainless steel reservoirs that allow operation with or without recirculation loop or cooling coil
  
• Sanitary pressure transducer with flush diaphragm and digital readout
  
• Autoclavable unit (sterilizable to 121°C)
  
• Spare interaction chambers
  
• Recirculation reservoir, 25 ml capacity (14 ml sample size; 12 ml recovery)
  
• Diamond interaction chamber
  
• Mechanical pressure gauge
  

Operating Principle

Microfluidics' homogenizers contain air-powered intensifier pumps designed to supply the desired pressure at a constant rate to the product stream. As the pump travels through its pressure stroke, it drives the product at constant pressure through precisely defined fixed-geometry microchannels within the interaction chamber.

As a result, the product stream accelerates to high velocities creating shear rates within the product stream that are orders of magnitude greater than any other conventional means. All of the product experiences identical processing conditions, producing the desired results, including: uniform particle and droplet size reduction (often submicron), deagglomeration and high yield cell disruption.