HC-8000 Laboratory Homogenizers

HC-8000 Sanitary Standard, Lightweight, Versatile, Easy-To-Use Homogenizers

Recommended for:

* Emulsions
* Dispersions
* Cosmetics
* Pharmaceuticals
* Liposomes
* Food and Beverage Products

Microfluidics produces patented homogenizers that combine high flow with high-pressure, fixed-geometry interaction chambers that impart high shear rates to product formulations. The HC-Series Homogenizers produce up to 8,000 psi with standard lab air, for premium results at an affordable cost.

Microfluidizer processor combines superior, scalable results with easy handling and in-line cleaning:

* Unique, wear-resistant interaction chamber - no moving parts
* Pressures to 8,000 psi
* Sample sizes of 250 ml
* Sanitary type 316 stainless steel construction
* In-line cleaning of high pressure tubing
* Durable plunger seal , offers wide compatibility range and extended seal life
* Air-powered and explosion-proof
* Portable, benchtop
* Process stream temperature range -15°F to 165°F (-25°C to 75°C)

Download HC-2000, 5000 & 8000 Lab Homogenizer product info as a PDF


HC-8000 Specifications

  • Pressure range 1,000 - 8,000 psi (70 to 550 bar)
  • Flowrate Range to 1,000 ml/min
  • Feed Temperature Range -15°F to 165°F (-25°C to 75°C)
  • Air Compressor Requirements 50 scfm @ 50 psi (dew point 0-35°F)
    15 hp (11 kw)
  • Sample Size 250 ml to continuous
  • Dimensions 23"L x 15"W x 23"H (58 x 38 x 58 cm)
  • Weight 59 lbs. (26.7 kg)

HC-8000 Series Homogenizer Standard Features
* Ceramic interaction chamber
* 316 stainless steel for all wetted product contact surfaces
* In-line cleaning high-pressure tubing
* UHMWPE plunger seals
* Pressure gauge (non-sanitary type)
* Viton O-rings and gaskets (in product contact only)
* Sanitary flush diaphragm pressure transducer with digital read out

HC-8000 Options
* Alternate seal designs for process temperatures to 350°F (135°C)
* Cooling coil
* 400 ml manual pressure feed reservoir
* Pressurized feed tank
* Selection of homogenizing modules
* Autoclavable air motor
* HC-8000-I: same as HC8000 except sanitary pressure transducer is replaced with a non-sanitary pressure gauge

Typical results achieved using Microfluidizer homogenizers

Sample PSI Passes Results & Comments
Liposomes with Dye Marker 4000 4 300 to 400 nm-size liposomes in 1 pass. Subsequent passes tightened the distribution.
Tomato Sauce 2000 1 Increased viscosity. Smoother, more homogenous sauce with improved mouthfeel.
Dairy Filling 3000 1 Superior emulsion. Replaced hand homogenizer.
Soya Milk 4000 1 Particle size reduced from .76 to .4 microns.
Vaccine adjuvants:

Water in Oil


1500


1


More uniform emulsions than competitive homogenizing equipment at comparable pressures.

Cell Rupture:

E.Coli

Mammalian Cells

5000

2000

3

1

90% rupture rate.

Effective rupture with easy separation of parasites from host cells.

Mustard 8000 1 Very smooth results with brighter color and higher sheen.

.

Operating Principle

Microfluidics' homogenizers contain air-powered intensifier pumps designed to supply the desired pressure at a constant rate to the product stream. As the pump travels through its pressure stroke, it drives the product at constant pressure through precisely defined fixed-geometry microchannels within the interaction chamber.

As a result, the product stream accelerates to high velocities creating shear rates within the product stream that are orders of magnitude greater than any other conventional means. All of the product experiences identical processing conditions, producing the desired results, including: uniform particle and droplet size reduction (often submicron), deagglomeration and high yield cell disruption.

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