Recommended for:
* Emulsions
* Dispersions
* Cosmetics
* Pharmaceuticals
* Liposomes
* Food and Beverage Products
Microfluidics produces patented homogenizers that combine high flow with high-pressure, fixed-geometry interaction chambers that impart high shear rates to product formulations. The HC-Series Homogenizers produce up to 8,000 psi with standard lab air, for premium results at an affordable cost.
Microfluidizer processor combines superior, scalable results with easy handling and in-line cleaning
- Unique, wear-resistant interaction chamber - no moving parts
- Pressures to 5,000 psi
- Sample sizes of 100 ml
- Sanitary type 316 stainless steel construction
- In-line cleaning of high pressure tubing
- Durable plunger seal, offers wide compatibility range and extended seal life
- Air-powered and explosion-proof
- Portable, benchtop
- Process stream temperature range -15°F to 165°F (-25°C to 75°C)
Download HC-2000, 5000 & 8000 Lab Homogenizer product info as a PDF
HC-5000 Specifications
- Pressure range 500 - 5000 psi (34 to 345 bar)
- Flowrate Range to 950 ml/min
- Feed Temperature Range -15°F to 165°F (-25°C to 75°C)
- Air Compressor Requirements 28 scfm @ 91 psi (dew point 0-35°F) 7.5 hp (5.6 kw)
- Sample Size 100 ml to continuous
- Dimensions 17"L x 17"W x 20"H (44 x 44 x 51 cm)
- Weight 37 lbs. (16.8 kg)
5000 Series Homogenizer Standard Features
- Ceramic interaction chamber
- 316 stainless steel for all wetted product contact surfaces
- In-line cleaning high-pressure tubing
- UHMWPE plunger seals
- Pressure gauge (non-sanitary type)
- Viton O-rings and gaskets (in product contact only)
HC-5000 Options
- Sanitary pressure transducer with microprocessor-based, digital-display indicator
- Cooling coil
- Autoclavable air motor
- 400 ml manual pressure feed reservoir
- Pressurized feed tank
- Selection of homogenizer modules for normal or high viscosity processing
Typical results achieved using Microfluidizer homogenizers
| Sample |
PSI |
Passes |
Results & Comments |
| Liposomes with Dye Marker |
4000 |
4 |
300 to 400 nm-size liposomes in 1 pass. Subsequent passes tightened the distribution. |
| Tomato Sauce |
2000 |
1 |
Increased viscosity. Smoother, more homogenous sauce with improved mouthfeel. |
| Dairy Filling |
3000 |
1 |
Superior emulsion. Replaced hand homogenizer. |
| Soya Milk |
4000 |
1 |
Particle size reduced from .76 to .4 microns. |
| Vaccine adjuvants:
Water in Oil
|
1500 |
1 |
More uniform emulsions than competitive homogenizing equipment at comparable pressures. |
| Cell Rupture:
E.Coli
Mammalian Cells
|
5000
2000
|
3
1
|
90% rupture rate.
Effective rupture with easy separation of parasites from host cells.
Mustard 8000 1 Very smooth results with brighter color and higher sheen.
|
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Operating Principle
Microfluidics' homogenizers contain air-powered intensifier pumps designed to supply the desired pressure at a constant rate to the product stream. As the pump travels through its pressure stroke, it drives the product at constant pressure through precisely defined fixed-geometry microchannels within the interaction chamber.
As a result, the product stream accelerates to high velocities creating shear rates within the product stream that are orders of magnitude greater than any other conventional means. All of the product experiences identical processing conditions, producing the desired results, including: uniform particle and droplet size reduction (often submicron), deagglomeration and high yield cell disruption.
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Processors
