Recommended for:

* Immiscible Liquid Emulsions
* Solids-in-Liquid Suspensions
* Liposomes
* Cell Disruption
* Particle Size Reduction for Submicron and Nano-sized particles
* Deagglomeration

The M-110EH-30 has been designed to reliably achieve continuous operating pressures to 30,000 psi. The processor maximizes the energy-per-unit fluid volume, resulting in uniform submicron particle and droplet sizes.
Utilizing Microfluidics’ fixed geometry diamond interaction chamber technology, and a ceramic (Zirconia) plunger, the M-110EH-30 is capable of processing a wide variety of fluids such as simple oil-in-water emulsions, solids-in-liquid suspensions, and cell disruptions, including the most difficult yeasts and plant cells, in 1-2 passes. What’s more, the process is repeatable and is guaranteed to scaleup to pilot and/or production volumes.

• Process pressure to 30,000 psi (2,070 bar)
  
• Flow rates to 320 ml/min at 30,000 psi
  
• Guaranteed scaleup to pilot and/or production
  
• Patented, wear resistant, diamond interaction chamber - no moving parts
  
• On-board heat exchanger for consistent discharge product temperature
  
• Ceramic (Zirconia) plunger for extended seal life
  
• Designed for clean-in-place with no disassembly required
  
• Available with steam-in-place (SIP) option
  
• Available explosion-proof option
  
• CE compliant (Europe)

Download M-110EH-30 product info as a PDF

M-110EH-30 Specifications

• Pressure Range up to 30,000 psi (2070 bar)
• Flow Rate up to 320 ml/min (optional 450 ml/min @ 25,000 psi)
• Maximum Feed Temperature 165°F (75°C)
• Holdup Volume 100 ml
• Utility Requirements:
  • Electrical 3 phase 60 Hz service, 208/230/460V, 5 HP (3.7 KW) (50 Hz European standard available)
  • Compressed Air 1 SCFM @ 50 psi (3.4 bar) with 35°F (2°C) max. dewpoint
  • Hydraulic Oil Heat Exchanger Cooling Water 2.5 gpm (9.5 lpm) minimum @ 85°F (29°C) max.
  • Product Outlet Heat Exchanger Cooling Water 5 gpm (18.9 lpm) @ 65°F (16°C)
• Minimum Sample Size 120 ml
• Dimensions 33”L x 34”W x 58”H (84 x 87 x 148 cm)
• Weight 450 lbs. (205 kg)
  

M-110EH-30 Standard Features

• Diamond interaction chamber with ceramic Auxiliary Processing Module (APM)
  
• Ceramic (Zirconia) plunger for extended seal life
  
• Stainless steel enclosure
  
• Electric-hydraulic power unit
  
• Gauges for measuring process pressure, hydraulic drive pressure, and hydraulic oil level and temperature
  
• Self-contained unit, mounted on locking casters for portability
  
• Flow rates to 320 ml/min @ 30,000 psi
  
• Minimum sample sizes as small as 120 ml
  
• Feed temperature to 165°F (75°C)
  
• TEFC (totally enclosed fan cooled) motor, starter, controls and power cord

M-110EH-30 Options

• 2 liter reservoir • 2 gallon pressure-type feed tank
  
• 2 liter pressure-type reservoir • Solvent seal quench system for 450 ml/min flow rate at 25,000 psi
  
• Sanitary flush diaphragm pressure transducer with digital readout • Additional interaction chamber set
  
• On-board air compressor for air switch activation • Steam sterility (or hot water) package
  
• Interaction Chamber cooling bath
  
• Explosion-proof design
  
  

Operating Principle

The M-110EH-30 contains an onboard 5 horsepower (3.7 kw) electric-hydraulic module that powers a single acting intensifier pump. The intensifier pump amplifies the hydraulic pressure to the selected level which, in turn, imparts that pressure to the product stream. Process pressures may be selected with the simple turn of a knob.

The intensifier pump is designed to supply the desired pressure at a constant rate to the product stream. As the pump travels through its pressure stroke, it drives the product at constant pressure through the interaction chamber. Within the chamber are specially designed fixed-geometry microchannels through which the product stream will accelerate to high velocities, creating high shear and impact forces that bring about the desired results as the high velocity product stream impinges on itself and on wear-resistant surfaces.

As the intensifier pump completes its pressure stroke, it reverses direction and draws in a new volume of product. At the end of the intake stroke, it reverses direction and again drives the product at constant pressure, repeating the process.

Upon exiting the interaction chamber, the product flows through an onboard heat exchanger which regulates the product to a desired temperature. At this point the product may be recirculated through the system for further processing or directed externally to the next step in the process.