Electric-Hydraulic Pilot Scale Processor For Continuous High-Shear Processing

Recommended for:

* Immiscible Liquid Emulsions
* Solids-in-Liquid Suspensions
* Submicron Particle Size Reduction
* Cell Disruption
* Deagglomeration

The M-210EH Series A, B and C Microfluidizer Processors are pilot-scale machines that provide the highest shear rates of all available mixers and homogenizers on the market today. Three models are available to provide the user with a broad choice of operating pressures and product flow rates. The M-210EH series machines maximize the energy-per-unit fluid volume, resulting in uniform submicron particle and droplet sizes.

Using Microfluidics’ fixed-geometry interaction chamber technology, each M-210EH model is easy to operate, and is capable of processing a wide variety of fluids ranging from simple oil-in water emulsions to highly abrasive solid-in-liquid suspensions.

The M-210EH machines are also highly efficient in deagglomeration and cell disruption..

Key benefits:

• Repeatable, uniform results with guaranteed scale-up to full production
• Maximum product yield — continuous or batch mode; the model M-210EH can produce 1.5 gpm

Key features:

• Double-acting intensifier pump provides near-perfect pressure profile for repeatable results
• Patented, wear-resistant interaction chamber technology maximizes energy-per-unit volume of product
• The M-210EH machines are also highly efficient in deagglomeration and cell disruption
• Highest shear rates of all available mixers and homogenizers
• Easy in-line cleaning and simple maintenance

Download M-210EH product info as a PDF

M-210EH Standard Features

• Dimensionally-Fixed Interaction Chamber Employs No Moving Parts — abrasion-resistant ceramic or diamond construction.
• Highly Durable Intensifier Pumping System —efficient at ultrahigh pressures.
• High-Pressure Plunger Seals and Check Valves —made to withstand abrasive and corrosive formulations. Both seals and check valves are accessible and can be replaced easily.
• Isolation Of The Process Fluid From The Hydraulic Fluid — prevents cross contamination.
• Coned and Threaded Tubing and Fittings — these connections provide a high degree of reliability and cleanability.
• Stainless Steel Frame and Enclosure — protects the high pressure components from damage, contains spills and features panels which are easily removable.
• Components Rated For Maximum Working Pressure of the Machine.
• Simple and Efficient Fluid Power Drive System.
• Materials of Construction — wetted parts of: 316S.S.,
• Tungsten Carbide, alumina (Al 2 O 3 ), Ultra high molecular weight polyethylene (UHMWPE), Teflon® (PTFE), polyetheretherketone (PEEK), 17.4 PH S.S., Nitronic 60, 15.5 PH S.S.

M-210EH Options

• Plunger Seals — Teflon® (PTFE) seals are available for high temperatures of up to 300°F
• Outlet heat exchanger
• Chamber Sets — additional sets of interaction chambers are available in different sizes or diamond interiors to suit application requirements
• Steam sterility package
• Ultra-Clean-In-Place (UCIP)
• Solvent seal quench
• Flush Diaphragm Pressure Transducer — for electronic readings of the system pressure
• Explosion-proof Motor — for hazardous environments
• Alternate Finishes — to meet sanitary standards
• CE compliance (Europe)
  

Operating Principle

Each M-210EH series machine contains an on-board 15 horsepower electric-hydraulic module that provides power to a double-acting intensifier pump. The intensifier pump amplifies the hydraulic pressure and, in turn, imparts that pressure to the product stream. Process pressures ranging from 2,500 to 30,000 psi may be selected with the simple turn of a knob.

The intensifier pump is designed to supply the desired pressure at a constant rate to the product stream. As the pump travels in one direction, it drives the product at constant pressure through the interaction chamber. Within the chamber are specially designed fixed-geometry microchannels through which the product accelerates to high velocities, creating shear and impact forces as the product stream impinges upon itself and on wear-resistant surfaces, bringing about the desired results.

As the intensifier pump continues its travel in one direction, a series of check valves allow product to be drawn into the opposite end of the pump. As the intensifier pump completes its stroke, it reverses direction and the new volume of product is pressurized repeating the process. This creates a constant flow of product at near constant pressure through the interaction chamber.

Upon exiting the interaction chamber, the product may be directed through an optional heat exchanger, recirculated through the system for further processing or directed externally to the next step in the process, bringing about the desired results.